Epirizole
Based on 1 Customer Validation
Epirizole (Mepirizole) is an orally active NSAID (nonsteroidal anti-inflammatory agent). Epirizole shows anti-inflammatory activity, and can be used in chronic rheumatoid arthritis research.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 18694-40-1
- Formula: C11H14N4O2
- Molecular Weight:234.26
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Orally Active Compound Library
HY-L061
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FDA Approved & Pharmacopeial Drug Library
HY-L066
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Human Metabolite Library
HY-L123
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Non-steroidal Anti-Inflammatory Compound Library
HY-L130
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Heterocyclic Compound Library
HY-L138
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Anti-Rheumatic Arthritis Compound Library
HY-L210
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Mass Spectrometry Human Metabolite Library
HY-L215
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MCE Kinase Hinge Binder Fragment Library
HY-L907
Biological Activity
Epirizole (1-1000 μM; 24 h) increases MDR1 mRNA expression in Caco-2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Caco-2 cells
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Concentration:1, 10, 100, and 1000 μM
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Incubation Time:24 hours
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Result:Increased the level of MDR1 mRNA expression.
Chemical Information
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CAS No. 18694-40-1
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Appearance Solid
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Molecular Weight 234.26
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Formula C11H14N4O2
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Color White to off-white
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SMILES
CC1=CC(OC)=NC(N2N=C(C)C=C2OC)=N1
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Synonyms
Mepirizole; DA-398
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 250 mg/mL (1067.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2688 mL | 21.3438 mL | 42.6876 mL | 106.7190 mL |
| 5 mM | 0.8538 mL | 4.2688 mL | 8.5375 mL | 21.3438 mL | |
| 10 mM | 0.4269 mL | 2.1344 mL | 4.2688 mL | 10.6719 mL | |
| 15 mM | 0.2846 mL | 1.4229 mL | 2.8458 mL | 7.1146 mL | |
| 20 mM | 0.2134 mL | 1.0672 mL | 2.1344 mL | 5.3360 mL | |
| 25 mM | 0.1708 mL | 0.8538 mL | 1.7075 mL | 4.2688 mL | |
| 30 mM | 0.1423 mL | 0.7115 mL | 1.4229 mL | 3.5573 mL | |
| 40 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6680 mL | |
| 50 mM | 0.0854 mL | 0.4269 mL | 0.8538 mL | 2.1344 mL | |
| 60 mM | 0.0711 mL | 0.3557 mL | 0.7115 mL | 1.7787 mL | |
| 80 mM | 0.0534 mL | 0.2668 mL | 0.5336 mL | 1.3340 mL | |
| 100 mM | 0.0427 mL | 0.2134 mL | 0.4269 mL | 1.0672 mL |
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