2. Inhibitory Antibodies
  3. Epoetin beta

Epoetin beta  (Synonyms: rhEPO; EPOCH; Genetical recombination)

Cat. No.: HY-114134 Purity: ≥95.0%
COA

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Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research.

For research use only. We do not sell to patients.

Epoetin beta Chemical Structure

Epoetin beta Chemical Structure

CAS No. : 122312-54-3

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2000 IU USD 1250 In-stock

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Based on 1 publication(s) in Google Scholar

Epoetin beta Related Antibodies

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Description

Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research[1].

In Vivo

Epoetin beta (rhEPO) (1000 IU/kg; s.c.; three times per week over 14 days) prevents anaemia and enhances the radiosensitivity of solid growing DS-sarcomas[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats, body weight 140-170 g[2]
Dosage: 1000 IU/kg
Administration: Subcutaneous injection, three times per week over 14 days starting 9 days before tumour implantation. Solid DS-sarcomas were induced by injecting DS-sarcoma cells (0.4 mL, approximately 104 cells/uL) subcutaneously into the hind food dorsum. A prolonged anaemia was induced in all animals by a single i.v. dose of carboplatin (45 mg/kg dissolved in isotonic saline at a concentration of 20 mg/mL) into the tail vein 3 days before tumour implantation.
Result: Prevented anaemia and significantly increased the radiosensitivity of solid growing DS-sarcomas, tumours showing pronounced hypoxia even under non-anaemic control conditions.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Epoetin beta]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: ≥95.0%

COA (231 KB)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epoetin beta122312-54-3rhEPO EPOCH Genetical recombinationOthersanaemiahaemoglobinhaematocritreticulocyte countserythropoietinInhibitorinhibitorinhibit

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