Disomotide
Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma.
For research use only. We do not sell to patients.
- CAS No.: 181477-43-0
- Formula: C47H74N10O14S
- Molecular Weight:1035.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
For Ag activation, PBMCs from immunized patients are cultured for 6 days with Disomotide (G209-2M) peptide (1 μM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 181477-43-0
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Molecular Weight 1035.21
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Formula C47H74N10O14S
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Synonyms
G209-2M; GP100:209-217(210M); MPS-22
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Sequence
Ile-Met-Asp-Gln-Val-Pro-Phe-Ser-Val
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Sequence Shortening
IMDQVPFSV
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9. [Content Brief]
[2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Disomotide Related Classifications
HY-105039 Related Classifications
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