IM-2
Based on 1 Customer Validation
IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- CAS No.: 2813269-89-3
- Formula: C29H35N7O10S
- Molecular Weight:673.69
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2813269-89-3
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Appearance Solid
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Molecular Weight 673.69
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Formula C29H35N7O10S
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Color White to off-white
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SMILES
OC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCC#CC1=CN=C(S(C)(=O)=O)N=C1)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (148.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (263 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4844 mL | 7.4218 mL | 14.8436 mL | 37.1091 mL |
| 5 mM | 0.2969 mL | 1.4844 mL | 2.9687 mL | 7.4218 mL | |
| 10 mM | 0.1484 mL | 0.7422 mL | 1.4844 mL | 3.7109 mL | |
| 15 mM | 0.0990 mL | 0.4948 mL | 0.9896 mL | 2.4739 mL | |
| 20 mM | 0.0742 mL | 0.3711 mL | 0.7422 mL | 1.8555 mL | |
| 25 mM | 0.0594 mL | 0.2969 mL | 0.5937 mL | 1.4844 mL | |
| 30 mM | 0.0495 mL | 0.2474 mL | 0.4948 mL | 1.2370 mL | |
| 40 mM | 0.0371 mL | 0.1855 mL | 0.3711 mL | 0.9277 mL | |
| 50 mM | 0.0297 mL | 0.1484 mL | 0.2969 mL | 0.7422 mL | |
| 60 mM | 0.0247 mL | 0.1237 mL | 0.2474 mL | 0.6185 mL | |
| 80 mM | 0.0186 mL | 0.0928 mL | 0.1855 mL | 0.4639 mL | |
| 100 mM | 0.0148 mL | 0.0742 mL | 0.1484 mL | 0.3711 mL |
IM-2 Related Classifications
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