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Cat. No.: HY-145081

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Pitnot-2

Name: Pitnot-2
Brand: MedChemExpress
SKU: HY-145081
Price: 135.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

Pitnot-2 is an inactive analog of Pitstop 2 (HY-115604), a clathrin inhibitor series. Pitnot-2 serves as a negative control in studies of clathrin-mediated endocytosis.

For research use only. We do not sell to patients.

Purity : 99.97%
CAS No.: 1576239-29-6
Formula: C₂₀H₁₃BrN₂OS
Molecular Weight:409.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pitnot-2 Chemical Structure

CAS No.: 1576239-29-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Pitnot-2 is an inactive analog of Pitstop 2 (HY-115604), a clathrin inhibitor series. Pitnot-2 serves as a negative control in studies of clathrin-mediated endocytosis^[1].

In Vitro

Pitnot-2 is an inactive analog of the clathrin inhibitor Pitstop 2; it is insoluble in water and can be dissolved in low-concentration DMSO for experimental use^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1576239-29-6
Appearance Solid
Molecular Weight 409.30
Formula C₂₀H₁₃BrN₂OS
Color Light yellow to yellow
SMILES

BrC(C=C1)=CC=C1/C=C2SC(NC3=CC=CC4=C3C=CC=C4)=NC\2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (122.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4432 mL

12.2160 mL

24.4320 mL

5 mM

0.4886 mL

2.4432 mL

4.8864 mL

10 mM

0.2443 mL

1.2216 mL

2.4432 mL

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Robertson MJ, et al. Synthesis of the Pitstop family of clathrin inhibitors. Nat Protoc. 2014;9(7):1592-1606.
[Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4432 mL	12.2160 mL	24.4320 mL	61.0799 mL
	5 mM	0.4886 mL	2.4432 mL	4.8864 mL	12.2160 mL
	10 mM	0.2443 mL	1.2216 mL	2.4432 mL	6.1080 mL
	15 mM	0.1629 mL	0.8144 mL	1.6288 mL	4.0720 mL
	20 mM	0.1222 mL	0.6108 mL	1.2216 mL	3.0540 mL
	25 mM	0.0977 mL	0.4886 mL	0.9773 mL	2.4432 mL
	30 mM	0.0814 mL	0.4072 mL	0.8144 mL	2.0360 mL
	40 mM	0.0611 mL	0.3054 mL	0.6108 mL	1.5270 mL
	50 mM	0.0489 mL	0.2443 mL	0.4886 mL	1.2216 mL
	60 mM	0.0407 mL	0.2036 mL	0.4072 mL	1.0180 mL
	80 mM	0.0305 mL	0.1527 mL	0.3054 mL	0.7635 mL
	100 mM	0.0244 mL	0.1222 mL	0.2443 mL	0.6108 mL

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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MCE Japan Authorized Agent:

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Pitnot-2

Biological Activity

Description

In Vitro

Chemical Information

Solvent & Solubility

In Vitro:

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

Pitnot-2 Related Classifications

HY-145081 Related Classifications

Bioz

Keywords

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