Complement Component 6
Complement component 6 (C6) is one of the terminal complement components that assemble the membrane attack complex (MAC). This single-chain plasma glycoprotein is built from repeated thrombospondin, LDL-receptor, and EGF-like modules arranged into canonical complement protein domains. Once C5b is generated on an activating surface, C6 binds C5b directly to form the stable C5b-6 intermediate, to which C7 subsequently attaches and commits the complex to membrane insertion. Inherited C6 deficiency, described in several populations worldwide, predisposes carriers to recurrent Neisseria meningitidis infections. Recombinant C6 and related terminal-pathway proteins are used to dissect MAC assembly in complement research.
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Complement Component 6 Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
