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Cat. No.: HY-145415

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W13

W13 is a potent MsbA inhibitor. W13 is an ATPase stimulator with an EC₅₀ of 5.5 µM.

For research use only. We do not sell to patients.

CAS No.: 1060518-03-7
Formula: C₃₀H₃₄N₄O₃
Molecular Weight:498.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

W13 Chemical Structure

CAS No.: 1060518-03-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

W13 is a potent MsbA inhibitor. W13 is an ATPase stimulator with an EC₅₀ of 5.5 µM^[1].

Chemical Information

CAS No. 1060518-03-7
Molecular Weight 498.62
Formula C₃₀H₃₄N₄O₃
SMILES

O=C(C1=CN(CC2=NC=CC=C2)C=C(C(N3CC4=C(CC3)C=CC=C4)=O)C1=O)NC5CCCCCCC5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. François A Thélot, et al. Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science. 2021 Oct 29;374(6567):580-585. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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