CDAP
Based on 1 Customer Validation
CDAP is an organic cyanylating reagent that can be used for preparation of solid phase affinity reagents, modification of protein thiols and nucleotide delivery. CDAP also activates polysaccharides with a variety of chemical properties. CDAP can be used to prepare conjugate vaccines and other immune reagents.
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- Pureza: 98.0%
- No. CAS: 59016-56-7
- Fòrmula: C8H10BF4N3
- Peso molecular:234.99
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Actividad biológica
CDAP can be used to activate a broad range of acidic, neutral and other classes of polysaccharides, which can then be clerivatized with diamines, dihydrazides or other functional groups in preparation for coupling to proteins[1].
Proteins can be directly conjugated to CDAP-activated polysaccharides, without the need for additional spacer molecules, thereby simplifying the preparation of conjugate vaccines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 59016-56-7
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Appearance Solid
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Peso molecular 234.99
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Fòrmula C8H10BF4N3
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Color White to off-white
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SMILES
CN(C)C1=CC=[N+](C=C1)C#N.F[B-](F)(F)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
DMSO : 100 mg/mL (425.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (267 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2554 mL | 21.2772 mL | 42.5545 mL | 106.3861 mL |
| 5 mM | 0.8511 mL | 4.2554 mL | 8.5109 mL | 21.2772 mL | |
| 10 mM | 0.4255 mL | 2.1277 mL | 4.2554 mL | 10.6386 mL | |
| 15 mM | 0.2837 mL | 1.4185 mL | 2.8370 mL | 7.0924 mL | |
| 20 mM | 0.2128 mL | 1.0639 mL | 2.1277 mL | 5.3193 mL | |
| 25 mM | 0.1702 mL | 0.8511 mL | 1.7022 mL | 4.2554 mL | |
| 30 mM | 0.1418 mL | 0.7092 mL | 1.4185 mL | 3.5462 mL | |
| 40 mM | 0.1064 mL | 0.5319 mL | 1.0639 mL | 2.6597 mL | |
| 50 mM | 0.0851 mL | 0.4255 mL | 0.8511 mL | 2.1277 mL | |
| 60 mM | 0.0709 mL | 0.3546 mL | 0.7092 mL | 1.7731 mL | |
| 80 mM | 0.0532 mL | 0.2660 mL | 0.5319 mL | 1.3298 mL | |
| 100 mM | 0.0426 mL | 0.2128 mL | 0.4255 mL | 1.0639 mL |