IAA65
IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 µM. IAA65 can be used for epilepsy research.
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- No. CAS: 2987139-96-6
- Fòrmula: C16H13F6NO2
- Peso molecular:365.27
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
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T-type calcium channel |
In Vitro
IAA65 (50 µM; differentiated ND7/23 cells) causes a significant reduction in the current density generated by T-type Ca2+ channel activation[1].
IAA65 (50 µM; differentiated ND7/23 cells) alters the steady-state inactivation of Cav3.2 and Cav3.3 T-type Ca2+ channels, which resulted in a significant increase in the inactivation recovery time of the channels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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No. CAS 2987139-96-6
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Peso molecular 365.27
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Fòrmula C16H13F6NO2
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SMILES
O=C(NC1=CC(CC(C)C1)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IAA65 Related Classifications
HY-150541 Related Classifications
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