L 743310
L 743310 is a non-peptide, selective antagonist of the human neurokinin hNK1 receptor, with high affinity for primate and cloned human hNK1 receptors and lower affinity for rodent NK1 receptors. L 743310 inhibits resiniferatoxin-induced plasma protein extravasation in guinea pig esophagus. L 743310 has a dose-dependent inhibitory effect on cisplatin-induced emesis.
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- No. CAS: 187724-86-3
- Fòrmula: C30H33BrF6N4O2
- Peso molecular:675.50
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
hNK1 receptor[1]
Chemical Information
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No. CAS 187724-86-3
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Peso molecular 675.50
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Fòrmula C30H33BrF6N4O2
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SMILES
C[N+]1(CC2)CCC2(NC(NC(CC3=CNC4=C3C=CC=C4)C(CCC5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)=O)=O)CC1.[Br-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L 743310 Related Classifications
HY-117952 Related Classifications
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