MK-4688
MK-4688 is an efficient inhibitor of the HDM2-p53 protein-protein interaction.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1616428-79-5
- Fòrmula: C28H32ClN7O3
- Peso molecular:550.05
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
122 nM
Compound: 56; MK-4688
|
Antiproliferative activity against human HCT-116 cells expressing wild-type p53 incubated for 72 hrs
Antiproliferative activity against human HCT-116 cells expressing wild-type p53 incubated for 72 hrs
|
[PMID: 34714078] |
Chemical Information
-
No. CAS 1616428-79-5
-
Peso molecular 550.05
-
Fòrmula C28H32ClN7O3
-
SMILES
C[C@@H](CC1)CC[C@H]1CN(C(N2CCO[C@H]3[C@H]2CCC3)=N4)C5=C4C=C(C(N6)=NOC6=O)N=C5C7=CC(Cl)=CN=C7
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)