Muzolimine
Based on 1 Customer Validation
Muzolimine (BAY-g 282) is a slow and long lasting diuresis agent. Muzolimine produces a diuresis in the loop of Henle and also shows anti-hypertensive and natriuresis effects. Muzolimine can be used for the research of cardiovascular disease.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.22%
- No. CAS: 55294-15-0
- Fòrmula: C11H11Cl2N3O
- Peso molecular:272.13
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
Muzolimine (10 μM-1 mM) dose-dependently inhibits ion transport in Ehrlich cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:3 male and 3 female dogs[1]
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Dosage:0, 2, 6, 8 and 18 mg/kg
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Administration:Oral gavage; 7 times per week for 3 months
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Result:Showed significant diuretic results, and increased the water intake of dogs.
Chemical Information
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No. CAS 55294-15-0
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Appearance Solid
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Peso molecular 272.13
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Fòrmula C11H11Cl2N3O
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Color Light yellow to yellow
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SMILES
CC(C1=CC(Cl)=C(Cl)C=C1)N2C(CC(N)=N2)=O
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Synonyms
BAY-g 2821; Edrul
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (367.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6747 mL | 18.3736 mL | 36.7471 mL | 91.8679 mL |
| 5 mM | 0.7349 mL | 3.6747 mL | 7.3494 mL | 18.3736 mL | |
| 10 mM | 0.3675 mL | 1.8374 mL | 3.6747 mL | 9.1868 mL | |
| 15 mM | 0.2450 mL | 1.2249 mL | 2.4498 mL | 6.1245 mL | |
| 20 mM | 0.1837 mL | 0.9187 mL | 1.8374 mL | 4.5934 mL | |
| 25 mM | 0.1470 mL | 0.7349 mL | 1.4699 mL | 3.6747 mL | |
| 30 mM | 0.1225 mL | 0.6125 mL | 1.2249 mL | 3.0623 mL | |
| 40 mM | 0.0919 mL | 0.4593 mL | 0.9187 mL | 2.2967 mL | |
| 50 mM | 0.0735 mL | 0.3675 mL | 0.7349 mL | 1.8374 mL | |
| 60 mM | 0.0612 mL | 0.3062 mL | 0.6125 mL | 1.5311 mL | |
| 80 mM | 0.0459 mL | 0.2297 mL | 0.4593 mL | 1.1483 mL | |
| 100 mM | 0.0367 mL | 0.1837 mL | 0.3675 mL | 0.9187 mL |
Muzolimine Related Classifications
HY-106616 Related Classifications
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