Salinazid
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Salinazid is an antituberculous compound.
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- Pureza: 99.62%
- No. CAS: 495-84-1
- Fòrmula: C13H11N3O2
- Peso molecular:241.25
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9c2 | EC50 |
18.2 μM
Compound: SIH
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Protection against t-BHP-induced oxidative injury in rat H9c2 cells assessed as increase in cell viability incubated for 10 mins followed by stimulation with t-BHP for 24 hrs by neutral red staining based assay
Protection against t-BHP-induced oxidative injury in rat H9c2 cells assessed as increase in cell viability incubated for 10 mins followed by stimulation with t-BHP for 24 hrs by neutral red staining based assay
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[PMID: 27187862] |
| H9c2 | IC50 |
28.9 μM
Compound: SIH
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Cytotoxicity against rat H9c2 cells assessed as decrease in cell viability after 72 hrs by neutral red staining based assay
Cytotoxicity against rat H9c2 cells assessed as decrease in cell viability after 72 hrs by neutral red staining based assay
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[PMID: 27187862] |
| HL-60 | IC50 |
5.7 μM
Compound: SIH
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Cytotoxicity against human HL60 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as decrease in cell viability after 72 hrs by MTT assay
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[PMID: 27187862] |
| MCF7 | IC50 |
12.4 μM
Compound: SIH
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Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by neutral red staining based assay
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by neutral red staining based assay
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[PMID: 27187862] |
| MT4 | CC50 |
2.52 μg/mL
Compound: 15
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Cytotoxicity against Homo sapiens (human) MT4 cells
Cytotoxicity against Homo sapiens (human) MT4 cells
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10.1007/s00044-011-9662-9 |
| MT4 | EC50 |
>2.52 μg/mL
Compound: 15
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Antiviral activity against Human immunodeficiency virus 1 IIIB infected human MT4 cells assessed as inhibition of virus-induced cytopathicity
Antiviral activity against Human immunodeficiency virus 1 IIIB infected human MT4 cells assessed as inhibition of virus-induced cytopathicity
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10.1007/s00044-011-9662-9 |
| MT4 | EC50 |
>2.52 μg/mL
Compound: 15
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Antiviral activity against Human immunodeficiency virus type 2 (ISOLATE ROD) infected human MT4 cells assessed as inhibition of virus-induced cytopathicity
Antiviral activity against Human immunodeficiency virus type 2 (ISOLATE ROD) infected human MT4 cells assessed as inhibition of virus-induced cytopathicity
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10.1007/s00044-011-9662-9 |
Chemical Information
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No. CAS 495-84-1
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Appearance Solid
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Peso molecular 241.25
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Fòrmula C13H11N3O2
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Color White to off-white
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SMILES
O=C(C1=CC=NC=C1)N/N=C/C2=CC=CC=C2O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : ≥ 250 mg/mL (1036.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1451 mL | 20.7254 mL | 41.4508 mL | 103.6269 mL |
| 5 mM | 0.8290 mL | 4.1451 mL | 8.2902 mL | 20.7254 mL | |
| 10 mM | 0.4145 mL | 2.0725 mL | 4.1451 mL | 10.3627 mL | |
| 15 mM | 0.2763 mL | 1.3817 mL | 2.7634 mL | 6.9085 mL | |
| 20 mM | 0.2073 mL | 1.0363 mL | 2.0725 mL | 5.1813 mL | |
| 25 mM | 0.1658 mL | 0.8290 mL | 1.6580 mL | 4.1451 mL | |
| 30 mM | 0.1382 mL | 0.6908 mL | 1.3817 mL | 3.4542 mL | |
| 40 mM | 0.1036 mL | 0.5181 mL | 1.0363 mL | 2.5907 mL | |
| 50 mM | 0.0829 mL | 0.4145 mL | 0.8290 mL | 2.0725 mL | |
| 60 mM | 0.0691 mL | 0.3454 mL | 0.6908 mL | 1.7271 mL | |
| 80 mM | 0.0518 mL | 0.2591 mL | 0.5181 mL | 1.2953 mL | |
| 100 mM | 0.0415 mL | 0.2073 mL | 0.4145 mL | 1.0363 mL |