TLD-1433
TLD-1433 is a ruthenium (II)-based water-soluble photodynamic compound. TLD-1433 inactivates enveloped viruses by inducing lipid peroxidation. TLD-1433 inactivates a variety of human pathogenic enveloped and non-enveloped viruses. TLD-1433 can be used in the research of viral infections and BCG-unresponsive non-muscle invasive bladder cancer.
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- No. CAS: 1471479-22-7
- Fòrmula: C49H38Cl2N8RuS3
- Peso molecular:1007.05
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
TLD-1433 inactivates herpes simplex virus type 1 and Vaccinia virus in a concentration-dependent manner, with photo-activation reducing effective doses (ED50 values of 2.4 nM and 92.3 nM respectively) compared to dark treatment[1].
TLD-1433 inactivates adenovirus type 5 and mammalian orthoreovirus type 1 Lang in a concentration-dependent manner, with photo-activation reducing effective doses (ED50 values of 1.8 μM and 5.4 μM respectively) compared to dark treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1471479-22-7
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Peso molecular 1007.05
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Fòrmula C49H38Cl2N8RuS3
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SMILES
CC1=CC=[N](C2=C1)[Ru+2]([N]3=CC=C4)([N](C5=C6)=CC=C6C)([N](C5=C7)=CC=C7C)([N](C2=C8)=CC=C8C)[N]9=CC=CC%10=C9C3=C4C%11=C%10NC(C%12=CC=C(C%13=CC=C(C%14=CC=CS%14)S%13)S%12)=N%11.[Cl-].[Cl-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLD-1433 Related Classifications
HY-156786 Related Classifications
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Keywords
- TLD-1433
- 1471479-22-7
- TLD1433
- TLD 1433
- Reactive Oxygen Species (ROS)
- Influenza Virus
- SARS-CoV
- HSV
- SARS coronavirus
- Herpes simplex virus
- Vaccinia virus
- human pathogenic enveloped viruses
- non-enveloped viruses
- Influenza A virus H1N1
- human coronavirus OC-43
- Zika virus
- bladder tumor
- lipid peroxidation
- herpes simplex virus type 1
- adenovirus type 5
- Inhibitor
- inhibitor
- inhibit