2. Anti-infection
  3. Bacterial Fungal
  4. Etaconazol

Etaconazol (Etaconazole) is an azole fungicide. Etaconazol possesses endocrine-disrupting potential and inhibits placental steroidogenesis by suppressing 3β-hydroxysteroid dehydrogenase (3β-HSD1). Etaconazol binds to the NAD+/steroid-binding site of the target enzyme and acts on both the free enzyme and enzyme-substrate complex to inhibit their activity.

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Etaconazol

Etaconazol Chemical Structure

CAS No. : 60207-93-4

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Etaconazol Related Antibodies

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Description

Etaconazol (Etaconazole) is an azole fungicide. Etaconazol possesses endocrine-disrupting potential and inhibits placental steroidogenesis by suppressing 3β-hydroxysteroid dehydrogenase (3β-HSD1). Etaconazol binds to the NAD+/steroid-binding site of the target enzyme and acts on both the free enzyme and enzyme-substrate complex to inhibit their activity[1].

In Vitro

Etaconazole (0-100 μM; 30 min) potently inhibits the activity of human placental microsomal 3β-HSD1, with an IC50 of 78 μM and a Ki of 88.9 μM[1].
Etaconazole (0-100 μM; 30 min) inhibits 3β-HSD4 activity in rat placental microsomes, with an IC50 of 102.6 μM and a Ki of 109.6 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Etaconazol Related Antibodies
Molecular Weight

328.19

Formula

C14H15Cl2N3O2
CAS No.
SMILES

ClC1=CC=C(C(Cl)=C1)C2(OCC(O2)CC)CN3N=CN=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Etaconazol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Etaconazol60207-93-4EtaconazoleBacterialFungalfungicide3β-HSD1Inhibitorinhibitorinhibit

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