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Cat. No.: HY-147844

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F8-S43-S3

F8-S43-S3 is an inhibitor of SARS-CoV-2 main protease, with an IC₅₀ of 9.69 μM.

For research use only. We do not sell to patients.

CAS No.: 1632320-78-5
Formula: C₁₂H₁₀N₄O₃S
Molecular Weight:290.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

F8-S43-S3 Chemical Structure

CAS No.: 1632320-78-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

F8-S43-S3 is an inhibitor of SARS-CoV-2 main protease, with an IC₅₀ of 9.69 μM^[1].

Chemical Information

CAS No. 1632320-78-5
Molecular Weight 290.30
Formula C₁₂H₁₀N₄O₃S
SMILES

O=[N+](C1=CC=C(C2=CC=C(/C=N/NC(N)=S)O2)C=C1)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dou X, et, al. Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease. Eur J Med Chem. 2022 Aug 5;238:114508. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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