FA-PEG5-Mal
Based on 1 Customer Validation
FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureté: 99.46%
- Formule: C35H45N9O12
- Masse moléculaire:783.78
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Masse moléculaire 783.78
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Formule C35H45N9O12
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Color Light yellow to yellow
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SMILES
O=C1C2=C(N=C(N1)N)N=CC(CNC3=CC=C(C=C3)C(N[C@@H](CCC(NCCOCCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)C(O)=O)=O)=N2
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Synonyms
Folic acid-PEG5-Mal
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
DMSO : 100 mg/mL (127.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2759 mL | 6.3793 mL | 12.7587 mL | 31.8967 mL |
| 5 mM | 0.2552 mL | 1.2759 mL | 2.5517 mL | 6.3793 mL | |
| 10 mM | 0.1276 mL | 0.6379 mL | 1.2759 mL | 3.1897 mL | |
| 15 mM | 0.0851 mL | 0.4253 mL | 0.8506 mL | 2.1264 mL | |
| 20 mM | 0.0638 mL | 0.3190 mL | 0.6379 mL | 1.5948 mL | |
| 25 mM | 0.0510 mL | 0.2552 mL | 0.5103 mL | 1.2759 mL | |
| 30 mM | 0.0425 mL | 0.2126 mL | 0.4253 mL | 1.0632 mL | |
| 40 mM | 0.0319 mL | 0.1595 mL | 0.3190 mL | 0.7974 mL | |
| 50 mM | 0.0255 mL | 0.1276 mL | 0.2552 mL | 0.6379 mL | |
| 60 mM | 0.0213 mL | 0.1063 mL | 0.2126 mL | 0.5316 mL | |
| 80 mM | 0.0159 mL | 0.0797 mL | 0.1595 mL | 0.3987 mL | |
| 100 mM | 0.0128 mL | 0.0638 mL | 0.1276 mL | 0.3190 mL |
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