FABP1-IN-1
Based on 1 publication(s) in Google Scholar
FABP1-IN-1 (44) is a selective FABP1 inhibitor, with an IC50 of 4.46 μM. FABP1-IN-1 (44) can be used for the research of NASH.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 3048021-44-6
- Formula: C30H25NO5
- Molecular Weight:479.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) FABP1-IN-1
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Biological Activity
IC50: 4.46 μM (FABP1), >30 μM (FABP3), >15 μM (FABP4)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3048021-44-6
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Appearance Solid
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Molecular Weight 479.52
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Formula C30H25NO5
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Color White to off-white
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SMILES
O=C(NC1=CC(C2=CC=CC(OCC3CC3)=C2)=CC(C(O)=O)=C1)C4=CC(OC5=CC=CC=C5)=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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FASEB J
FABP5 regulates ROS-NLRP3 inflammasome in glutamate-induced retinal excitotoxic glaucomatous model. [Abstract]2025 Jan 15;39(1):e70281. PMID: 39792326
Solvent & Solubility
DMSO : 125 mg/mL (260.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0854 mL | 10.4271 mL | 20.8542 mL | 52.1355 mL |
| 5 mM | 0.4171 mL | 2.0854 mL | 4.1708 mL | 10.4271 mL | |
| 10 mM | 0.2085 mL | 1.0427 mL | 2.0854 mL | 5.2135 mL | |
| 15 mM | 0.1390 mL | 0.6951 mL | 1.3903 mL | 3.4757 mL | |
| 20 mM | 0.1043 mL | 0.5214 mL | 1.0427 mL | 2.6068 mL | |
| 25 mM | 0.0834 mL | 0.4171 mL | 0.8342 mL | 2.0854 mL | |
| 30 mM | 0.0695 mL | 0.3476 mL | 0.6951 mL | 1.7378 mL | |
| 40 mM | 0.0521 mL | 0.2607 mL | 0.5214 mL | 1.3034 mL | |
| 50 mM | 0.0417 mL | 0.2085 mL | 0.4171 mL | 1.0427 mL | |
| 60 mM | 0.0348 mL | 0.1738 mL | 0.3476 mL | 0.8689 mL | |
| 80 mM | 0.0261 mL | 0.1303 mL | 0.2607 mL | 0.6517 mL | |
| 100 mM | 0.0209 mL | 0.1043 mL | 0.2085 mL | 0.5214 mL |