1. Protein Tyrosine Kinase/RTK
  2. FAK
  3. FAK-IN-8

FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 µM). FAK-IN-8 has good anti-proliferative activity and can be used in cancer research.

For research use only. We do not sell to patients.

FAK-IN-8 Chemical Structure

FAK-IN-8 Chemical Structure

CAS No. : 1374959-91-7

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FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 µM). FAK-IN-8 has good anti-proliferative activity and can be used in cancer research[1].

IC50 & Target[1]


5.32 μM (IC50)

In Vitro

FAK-IN-8 (0-10 µM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: MCF-7 and B16-F10 cells
Concentration: 0-10 µM
Incubation Time: 48 h
Result: Exhibited anti-proliferative activity against MCF-7 and B16-F10 cells with IC50 values of 3.57 and 3.52 µM, respectively.
Molecular Weight







Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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FAK-IN-8 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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