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Cat. No.: HY-117478

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FE-999024

(Synonyms: CH-2856)

FE-999024 (CH-2856) is a specific tissue kallikrein inhibitor. FE-999024 can inhibit cancer cells invasion with a maximum of 39%. FE-999024 can reduce eosinophilia in a model of allergic inflammation. FE-999024 can be used for the researches of cancer, inflammation and immunology.

For research use only. We do not sell to patients.

CAS No.: 168825-65-8
Formula: C₂₆H₃₁ClN₆O₂
Molecular Weight:495.02

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

FE-999024 Chemical Structure

CAS No.: 168825-65-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Kallikrein Isoforms :

Chemical Information

CAS No. 168825-65-8
Molecular Weight 495.02
Formula C₂₆H₃₁ClN₆O₂
SMILES

ClC(C=C1)=CC=C1C[C@@H](N)C(N[C@H](C(NCCCNC(N)=N)=O)CC2=CC=CC3=C2C=CC=C3)=O
Synonyms

CH-2856
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wolf WC, et al. A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness. Am J Pathol. 2001 Nov;159(5):1797-805. [Content Brief]

[2]. Evans DM, et al. Synthetic inhibitors of human tissue kallikrein. Immunopharmacology. 1996 May;32(1-3):117-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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