Ferroptosis-IN-20

Ferroptosis-IN-20 (Compound 34a) is a Ferroptosis inhibitor (EC50: 24.2 nM) targeting voltage-dependent anion channel (VDAC). Ferroptosis-IN-20 inhibits VDAC oligomerization and lipid peroxidation. Ferroptosis-IN-20 reduces content of ROS, attenuates TFR1-mediated iron uptake, inhibits Fe2+ level and restores glutathione (GSH) level. Ferroptosis-IN-20 alleviates Folic acid (HY-16637)-induced acute kidney injury (AKI).

For research use only. We do not sell to patients.

  • Formula: C32H29FN2O4
  • Molecular Weight:524.58
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All VDAC Isoforms

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100 mg

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