Flotufolastat
Flotufolastat is a prostate-specific membrane antigen (PSMA) modulator. Flotufolastat is also a radiodiagnostic agent used in prostate cancer imaging. Flotufolastat can be used in research on prostate cancer and other cancers.
For research use only. We do not sell to patients.
- CAS No.: 2305060-41-5
- Formula: C63H99FN12O25Si
- Molecular Weight:1471.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2305060-41-5
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Molecular Weight 1471.61
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Formula C63H99FN12O25Si
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SMILES
CC(C)(C)[Si](F)(C1=CC=C(C=C1)C(NC[C@@H](NC(CC[C@H](N2CCN(CCN(CCN(CC2)CC(O)=O)CC(O)=O)CC(O)=O)C(O)=O)=O)C(N[C@@H](C(O)=O)CCCCNC(CCC(NCCC[C@H](C(O)=O)NC(CC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)=O)=O)C(C)(C)C
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Synonyms
rhPSMA-7.3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Heo YA. Flotufolastat F 18: Diagnostic First Approval. Mol Diagn Ther. 2023 Sep;27(5):631-636. [Content Brief]
[2]. Vogel MME, et al. Biochemical failure-free survival of 18F-rhPSMA-7 and 18F-flotufolastat PET-guided salvage radiotherapy for patients with recurrent prostate cancer. Sci Rep. 2025 Jan 17;15(1):2234. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)