FLT3-IN-32 TFA
FLT3-IN-32 TFA is a potent FLT3 inhibitor with an IC50s of 2.40 nM and 3.83 nM against FLT3-ITD and FLT3-D835Y. FLT3-IN-32 TFA inhibits proliferation/survival of human MV4-11 cells with an IC50 of 0.07 nM. FLT3-IN-32 TFA can be used for the study of acute myeloid leukemia (AML).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3047195-49-0
- Fòrmula: C30H30F3N5O7
- Peso molecular:629.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
FLT3-IN-32 TFA (Compound 29b) exhibits antiproliferative activity against EOL-1 (IC50 = 0.02 nM), MOLM-13 (IC50 = 0.20 nM), MONO-MAC-1 (IC50 = 100 nM) and MONO-MAC-6 (IC50 = 0.65 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3047195-49-0
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Peso molecular 629.58
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Fòrmula C30H30F3N5O7
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SMILES
O=C(NC1=CC2=C(OC(C(C3=CC4=C(CN(C)C)C(O)=CC=C4N3)=O)=C2)C=C1)NC5=NOC(C(C)(C)C)=C5.O=C(O)C(F)(F)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FLT3-IN-32 TFA Related Classifications
HY-174437A Related Classifications
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