FLT3-ITD-IN-2
FLT3-ITD-IN-2 (Compound A1) is an inhibitor for FLT3-ITD kinase with an IC50 of 2.12 nM. FLT3-ITD-IN-2 inhibits the proliferation of FLT3-dependent human AML cell line MOLM-13 with an IC50 of 25.65 nM. FLT3-ITD-IN-2 exhibits antitumor efficacy against acute myeloid leukemia.
For research use only. We do not sell to patients.
- Formula: C39H50N8O6
- Molecular Weight:726.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 726.86
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Formula C39H50N8O6
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SMILES
O=C([C@@]12[C@@H]3[C@@H]4[C@H]1[C@H]5[C@]4(C(OC)=O)[C@H]3[C@@H]25)N6CCN(C7CCN(C8=C(OC)C=C(NC9=C(C(N)=O)N=C(CC)C(NC%10CCOCC%10)=N9)C=C8)CC7)CC6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)