FLT3/ITD-IN-5
FLT3/ITD-IN-5 (Example 6) is an orally active FLT3 and FLT3-ITD inhibitor, with IC50 values of 0.088 and 0.348 nM, respectively. FLT3/ITD-IN-5 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3023632-62-1
- Formula: C23H25N7O2
- Molecular Weight:431.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 3023632-62-1
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Molecular Weight 431.49
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Formula C23H25N7O2
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SMILES
CCC1=C(C(C2=O)=NN1C)/C=C/C3=NNC4=CC=C(C(C=N5)=C(OCCN2C)N5C)C=C34
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)