FPPS-IN-2
FPPS-IN-2 (compound 4a) is a potent and orally active HFPPS inhibitor with an IC50 value of 1.108 µM. FPPS-IN-2 has the potential for the research of osteoporosis.
For research use only. We do not sell to patients.
- Formula: C24H26O6
- Molecular Weight:410.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 1.108 µM (HFPPS)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:200-250 g, Female Wistar rats[1]
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Dosage:0.1, 1, 10 mg/kg
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Administration:P.o.; daily for 8 weeks
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Result:Increased the osteocalcin level only with the 1, and 10 mg/kg doses, reduced urinary calcium.
Chemical Information
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Molecular Weight 410.46
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Formula C24H26O6
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SMILES
COC1=CC(/C=C/C(C)=O)=CC=C1OCCOC2=CC=C(/C=C/C(C)=O)C=C2OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)