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Cat. No.: HY-19370R

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FPS-ZM1 (Standard)

FPS-ZM1 (Standard) is the analytical standard of FPS-ZM1 (HY-19370). This product is intended for research and analytical applications. FPS-ZM1 is a high-affinity and BBB-permeable RAGE inhibitor with a K_i of 25 nM.

For research use only. We do not sell to patients.

CAS No.: 945714-67-0
Formula: C₂₀H₂₂ClNO
Molecular Weight:327.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

FPS-ZM1 (Standard) Chemical Structure

CAS No.: 945714-67-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 945714-67-0
Molecular Weight 327.85
Formula C₂₀H₂₂ClNO
SMILES

ClC1=CC=C(C(N(C2CCCCC2)CC3=CC=CC=C3)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Deane R, et al. A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest. 2012 Apr;122(4):1377-92. [Content Brief]

[2]. Hong Y, et al. Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus. Neurochem Res. 2016 May;41(5):1192-9. [Content Brief]

[3]. Lian YJ, et al. Ds-HMGB1 and fr-HMGB induce depressive behavior through neuroinflammation in contrast to nonoxid-HMGB1. Brain Behav Immun. 2017 Jan;59:322-332. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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