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Cat. No.: HY-174224

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Amb929

(Synonyms: ZINC000002782982)

Amb929 (ZINC000002782982), a nsp3 ligand, is an anti-SARS-CoV-2 agent. Amb929 inhibits SARS-CoV2-mNG replication in VeroE6 cells with an EC₅₀ of 34.7 µM. Amb929 has limited and moderate cytotoxicity for VeroE6 cells (CC₅₀: 281 µM). Amb929 also inhibits SARS-CoV-2-mNG replication in Human Airway Epithelium (HAE).

For research use only. We do not sell to patients.

CAS No.: 438196-25-9
Formula: C₂₉H₂₇N₃O₄S
Molecular Weight:513.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Amb929 Chemical Structure

CAS No.: 438196-25-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 438196-25-9
Molecular Weight 513.61
Formula C₂₉H₂₇N₃O₄S
SMILES

CC(C)COC1=CC(C2=NC3=CC=CC=C3C(C(NC(NC4=CC=C(C(OC)=O)C=C4)=S)=O)=C2)=CC=C1
Synonyms

ZINC000002782982
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mathilde Galais, et al. Highly potent antiviral drug candidates targeting SARS-CoV-2 nsp3 and nsp5. bioRxiv 2025.04.28.650947.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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