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Cat. No.: HY-189707

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CPD3

Name: CPD3
Brand: MedChemExpress
SKU: HY-189707
Availability: PreOrder

(Synonyms: Pym-PEG8-VA-PAB-Exatecan)

CPD3 (Pym-PEG8-VA-PAB-Exatecan) is an ADC linker-payload conjugate composed of a pym-PEG8-VA-PAB linker coupled to the cytotoxic payload Exatecan (HY-13631). CPD3 can be used for ADC synthesis.

For research use only. We do not sell to patients.

CAS No.: 3124004-50-5
Formula: C₆₅H₈₄FN₉O₂₀S
Molecular Weight:1362.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CPD3 Chemical Structure

CAS No.: 3124004-50-5

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Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

CPD3 (Pym-PEG8-VA-PAB-Exatecan) is an ADC linker-payload conjugate composed of a pym-PEG8-VA-PAB linker coupled to the cytotoxic payload Exatecan (HY-13631)^[1]. CPD3 can be used for ADC synthesis^[1].

All Drug-Linker Conjugates for ADC Isoforms :

In Vitro

The drug-linker conjugate of an antibody-drug conjugate (ADC) consists of an active cytotoxic drug and an appropriate linker. After conjugation with a monoclonal antibody, these conjugates are used to prepare ADCs, which are highly selective and cytotoxic targeted drugs against cancer cells.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

CAS No. 3124004-50-5
Molecular Weight 1362.47
Formula C₆₅H₈₄FN₉O₂₀S
SMILES

O=C(C1=CN=C(S(C)(=O)=O)N=C1)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O
Synonyms

Pym-PEG8-VA-PAB-Exatecan
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. LIU, Shaoqi, et al. CAIX-TARGETED SINGLE-DOMAIN ANTIBODIES, BISPECIFIC ANTIBODIES, ANTIBODY-DRUG CONJU-GATES, AND USE THEREOF. WO2026158439A1. 30.07.2026.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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