CSF1
CSF1 is a silicon-rhodamine-based, fluorescence-activatable probe with selectivity for Cu+. CSF1 colocalizes with the endoplasmic reticulum in live cells.
For research use only. We do not sell to patients.
- CAS No.: 2158211-22-2
- Formula: C39H51F3N2O2S4Si
- Molecular Weight:793.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
CSF1 serves as a fluorescent sensor for the specific recognition of Cu+ in aqueous buffer systems, with a Kd value of 0.49 pM, and its fluorescence response increases 17-fold upon binding to Cu+[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2158211-22-2
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Molecular Weight 793.18
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Formula C39H51F3N2O2S4Si
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SMILES
CCSCCSCCN(CC1=CC=C(C(C(F)(F)F)=C1)C2=C3C=CC(C=C3[Si](C)(C4=C2C=CC(N5CCOCC5)=C4)C)=O)CCSCCSCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)