FW-1
FW-1 is a type I inhibitor for FLT3 with IC50 of ca. 1 μM. FW-1 exhibits cytotoxicity in FLT3 mutated AML cell. FW-1 arrests the cell cycle at G0/G1 phase, and induces apoptosis in cell MV4-11 and MOLM-13.
For research use only. We do not sell to patients.
- Formula: C24H27N7O
- Molecular Weight:429.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 429.52
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Formula C24H27N7O
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SMILES
NC1=NOC2=NC(NC3=CC=C(CN4CCN(C)CC4)C=C3)=CC(NC5=CC=CC=C5)=C21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)