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Cat. No.: HY-W010612

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Hydantoin

Name: Hydantoin
Brand: MedChemExpress
SKU: HY-W010612
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Hydantoin is an imidazolidine-2,4-dione and serves as the parent nucleus of the antiepileptic agent Phenytoin (HY-B0448).

For research use only. We do not sell to patients.

CAS No.: 461-72-3
Formula: C₃H₄N₂O₂
Molecular Weight:100.08

Storage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Hydantoin Chemical Structure

CAS No.: 461-72-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Hydantoin is an imidazolidine-2,4-dione and serves as the parent nucleus of the antiepileptic agent Phenytoin (HY-B0448)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MRC5	IC₅₀	>100 μM Compound: 1a	Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay	[PMID: 38484804]

In Vitro

Hydantoin moieties in crystallized derivatives exhibit diverse hydrogen-bonding networks, with the centrosymmetric chain-of-rings arrangement observed in 10% of the studied structures, and the less-charged O4 atom frequently unused in hydrogen bonding^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 461-72-3
Appearance Solid
Molecular Weight 100.08
Formula C₃H₄N₂O₂
Color White to off-white
SMILES

O=C1NC(=O)CN1
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yu F L, et al. Hydantoin and hydrogen-bonding patterns in hydantoin derivatives[J]. Crystal Structure Communications, 2004, 60(10): o714-o717.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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