ABD56
ABD56 is a compound that induces osteoclast apoptosis and has the activity of inhibiting osteoclast formation and inducing apoptosis. ABD56 can inhibit osteoclast formation and induce apoptosis, and its mechanism is related to the inhibition of NFκB and ERK pathways.
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- CAS No.: 521294-19-9
- Formule: C17H18O3
- Masse moléculaire:270.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
>200 μM
Compound: 67, ABD56
|
Effect on apoptosis of hepatocyte
Effect on apoptosis of hepatocyte
|
[PMID: 17149877] |
| Osteoblast | IC50 |
>100 μM
Compound: 67, ABD56
|
Effect on apoptosis of osteoblast
Effect on apoptosis of osteoblast
|
[PMID: 17149877] |
| Osteoclast | IC50 |
9 μM
Compound: 67, ABD56
|
Inhibition of mouse osteoclast survival
Inhibition of mouse osteoclast survival
|
[PMID: 17149877] |
Chemical Information
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CAS No. 521294-19-9
-
Masse moléculaire 270.32
-
Formule C17H18O3
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SMILES
O=C(OCCCCO)C1=CC=C(C=C1)C2=CC=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)