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Cat. No.: HY-117457

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BPIC

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1444382-92-6
Formule: C₂₇H₂₀N₂O₅
Masse moléculaire:452.46

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

BPIC Chemical Structure

CAS No.: 1444382-92-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals^[1].

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
CCRF S-180	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HeLa	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HepG2	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HL-60	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HT-29	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
K562	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
SH-SY5Y	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]

Chemical Information

CAS No. 1444382-92-6
Masse moléculaire 452.46
Formule C₂₇H₂₀N₂O₅
SMILES

O=C(C1=C(O)C=CC(C2=NC(C(OCC3=CC=CC=C3)=O)=CC4=C2NC5=C4C=CC=C5)=C1)OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shan Li, et al. BPIC: A novel anti-tumor lead capable of inhibiting inflammation and scavenging free radicals. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1146-50. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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BPIC

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BPIC Related Classifications

HY-117457 Related Classifications