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United States

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Cat. No.: HY-180223

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FXIa-IN-17

FXIa-IN-17 (Compound FE12) is a selective FXIa inhibitor with an IC₅₀ of 4.4 nM. FXIa-IN-17 effectively inhibits thrombus formation.

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Formule: C₃₃H₃₂ClF₄N₉O₆S
Masse moléculaire:794.18

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

FXIa-IN-17 Chemical Structure

Stock

Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

FXIa-IN-17 (Compound FE12) is a selective FXIa inhibitor with an IC₅₀ of 4.4 nM. FXIa-IN-17 effectively inhibits thrombus formation^[1].

IC₅₀ & Target

IC₅₀: 4.4 nM (FXIa)^[1]

Chemical Information

Masse moléculaire 794.18
Formule C₃₃H₃₂ClF₄N₉O₆S
SMILES

ClC(C=C1C(C(OC)=CN2[C@@H](CC)C(NC3=CC=C(C4=NN=C(CN5CCN(S(C)(=O)=O)CC5)O4)C(F)=C3)=O)=CC2=O)=CC=C1N6N=NC(C(F)(F)F)=C6
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wu J, et al. Design, synthesis and biological evaluation of novel FXIa inhibitors featuring five-membered heterocycles as P2' fragments. Eur J Med Chem. 2026 Feb 5;303:118457. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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