1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor
  3. GABAA receptor agent 1

GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity.

For research use only. We do not sell to patients.

GABAA receptor agent 1 Chemical Structure

GABAA receptor agent 1 Chemical Structure

CAS No. : 1571-87-5

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 170 In-stock
Solution
10 mM * 1 mL in DMSO USD 170 In-stock
Solid
5 mg USD 155 In-stock
10 mg USD 248 In-stock
25 mg USD 495 In-stock
50 mg USD 792 In-stock
100 mg USD 1185 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity[1].

In Vivo

GABAA receptor agent 1 (30 mg/kg; intraperitoneal) inhibits the maximum electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions in swiss albino rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

273.67

Formula

C13H8ClN3O2

CAS No.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

O=[N+](C1=CC=C2N=C(C3=CC=C(Cl)C=C3)NC2=C1)[O-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (304.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6540 mL 18.2702 mL 36.5404 mL
5 mM 0.7308 mL 3.6540 mL 7.3081 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6540 mL 18.2702 mL 36.5404 mL 91.3509 mL
5 mM 0.7308 mL 3.6540 mL 7.3081 mL 18.2702 mL
10 mM 0.3654 mL 1.8270 mL 3.6540 mL 9.1351 mL
15 mM 0.2436 mL 1.2180 mL 2.4360 mL 6.0901 mL
20 mM 0.1827 mL 0.9135 mL 1.8270 mL 4.5675 mL
25 mM 0.1462 mL 0.7308 mL 1.4616 mL 3.6540 mL
30 mM 0.1218 mL 0.6090 mL 1.2180 mL 3.0450 mL
40 mM 0.0914 mL 0.4568 mL 0.9135 mL 2.2838 mL
50 mM 0.0731 mL 0.3654 mL 0.7308 mL 1.8270 mL
60 mM 0.0609 mL 0.3045 mL 0.6090 mL 1.5225 mL
80 mM 0.0457 mL 0.2284 mL 0.4568 mL 1.1419 mL
100 mM 0.0365 mL 0.1827 mL 0.3654 mL 0.9135 mL
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GABAA receptor agent 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GABAA receptor agent 1
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HY-133486
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