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Cat. No.: HY-N12743

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Farobin A

Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α.

For research use only. We do not sell to patients.

CAS No.: 1245447-08-8
Formula: C₂₇H₃₀O₁₄
Molecular Weight:578.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Farobin A Chemical Structure

CAS No.: 1245447-08-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Farobin A (compound 3) displays moderate antibacterial activity against Streptococcus mutans ATCC 25175 (inhibition rates of 28 %,) and Streptococcus sobrinus ATCC 33478 (inhibition rate of 26 %), at a concentration of 100 μg/mL^[1].
In RAW264.7 cells, when the lipopolysaccharide (LPS) (HY-D1056) stimulation concentration is 2463.9 pg/mL and Farobin A is treated at a concentration of 100 μg/mL, Farobin A decreases IL-6 production to 1051.8 pg/mL. With an LPS stimulation concentration of 14,644.8 pg/mL and the treatment with Farobin A at a concentration of 100 μg/mL, Farobin A reduces TNF-α production to 9606 pg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1245447-08-8
Molecular Weight 578.52
Formula C₂₇H₃₀O₁₄
SMILES

OC1=C2C(OC(C3=CC(O)=C(C=C3)O)=CC2=O)=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C1[C@H]5C[C@@H]([C@H]([C@H](O5)C)O)O
Structure Classification
- Flavonoids
- Flavones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hui Tan, et al. The discovery of an anti-inflammatory monoterpenoid, neoroseoside from the Zea mays. Bioorg Med Chem Lett. 2024 Jun 1:105:129737. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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