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United States

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Referencia número: HY-161418

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1-NBX

1-NBX is a potent and selective A₁R ligand. 1-NBX exhibits significantly improved A₁R affinity with with a K_i of 2.6 nM and lower affinity for the A₂A receptor with a K_i of 164 nM.

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Fòrmula: C₁₈H₂₅FN₄O₂
Peso molecular:348.42

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

1-NBX Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

1-NBX is a potent and selective A₁R ligand. 1-NBX exhibits significantly improved A₁R affinity with with a K_i of 2.6 nM and lower affinity for the A₂A receptor with a K_i of 164 nM^[1].

Ver todos los productos específicos de isoformas Adenosine Receptor :

Chemical Information

Peso molecular 348.42
Fòrmula C₁₈H₂₅FN₄O₂
SMILES

O=C1C2=C(N=C([C@]34CC[C@@H](C4)CC3)N2)N(CCCF)C(N1CCC)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Swen Humpert, et al. 8-Bicycloalkyl-CPFPX derivatives as potent and selective tools for in vivo imaging of the A1 adenosine receptor. Eur J Med Chem. 2024 Apr 6:271:116380. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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1-NBX

Ver todos los productos específicos de isoformas Adenosine Receptor

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

1-NBX Related Classifications

HY-161418 Related Classifications

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Keywords

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