2′-Hydroxygenistein
Based on 2 publication(s) in Google Scholar
2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively.
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- Pureza: 99.58%
- No. CAS: 1156-78-1
- Fòrmula: C15H10O6
- Peso molecular:286.24
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Actividad biológica
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Publications Citing Use of MedChemExpress (MCE) 2′-Hydroxygenistein
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| N9 | IC50 |
>30 μM
Compound: 2
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Inhibitory effect of compound on the accumulation of NO2 in the culture media of N9 cells in response to LPS/IFN-gamma
Inhibitory effect of compound on the accumulation of NO2 in the culture media of N9 cells in response to LPS/IFN-gamma
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[PMID: 15013012] |
| RAW | IC50 |
>30 μM
Compound: 2
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Inhibitory effect of compound on the accumulation of NO2 in the culture media of RAW 264.7 cells in response to LPS
Inhibitory effect of compound on the accumulation of NO2 in the culture media of RAW 264.7 cells in response to LPS
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[PMID: 15013012] |
| RAW264.7 | IC50 |
>1 μM
Compound: 18
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Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay
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[PMID: 29932657] |
Chemical Information
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No. CAS 1156-78-1
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Appearance Solid
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Peso molecular 286.24
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Fòrmula C15H10O6
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Color Off-white to light yellow
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SMILES
O=C1C(C2=CC=C(O)C=C2O)=COC3=CC(O)=CC(O)=C13
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Food Chem
Effects of sun drying combined with baking processes on the flavor quality of Chongqing Tuocha raw tea. [Abstract]2025 Dec 30:497:146992. PMID: 41285060 -
Food Chem
Flavonoid-mediated metabolic underpinning quality variation in red bud-sport pear mutants. [Abstract]2025 Oct 15:489:144992. PMID: 40466530
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2′-Hydroxygenistein Related Classifications
HY-N1735 Related Classifications
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