2-Methoxycinnamic acid
Based on 1 Customer Validation
2-Methoxycinnamic acid is an active compound. 2-Methoxycinnamic acid can be isolated from sour wampee varieties. 2-Methoxycinnamic acid non-competitively inhibits mushroom Tyrosinase-catalyzed L-DOPA oxidation with an ID50 of 0.34 mM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.94%
- No. CAS: 6099-03-2
- Fòrmula: C10H10O3
- Peso molecular:178.19
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-107369
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CajaninAnti-melanogenic Agent -
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4-Butylresorcinol (Standard)Tyrosinase Inhibitor -
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D-TyrosineMelanogenesis Inhibitor
Actividad biológica
Descripciòn
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 6099-03-2
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Appearance Solid
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Peso molecular 178.19
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Fòrmula C10H10O3
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Color White to off-white
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SMILES
O=C(O)/C=C/C1=CC=CC=C1OC
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (561.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (14.03 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (282 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6120 mL | 28.0599 mL | 56.1199 mL | 140.2997 mL |
| 5 mM | 1.1224 mL | 5.6120 mL | 11.2240 mL | 28.0599 mL | |
| 10 mM | 0.5612 mL | 2.8060 mL | 5.6120 mL | 14.0300 mL | |
| 15 mM | 0.3741 mL | 1.8707 mL | 3.7413 mL | 9.3533 mL | |
| 20 mM | 0.2806 mL | 1.4030 mL | 2.8060 mL | 7.0150 mL | |
| 25 mM | 0.2245 mL | 1.1224 mL | 2.2448 mL | 5.6120 mL | |
| 30 mM | 0.1871 mL | 0.9353 mL | 1.8707 mL | 4.6767 mL | |
| 40 mM | 0.1403 mL | 0.7015 mL | 1.4030 mL | 3.5075 mL | |
| 50 mM | 0.1122 mL | 0.5612 mL | 1.1224 mL | 2.8060 mL | |
| 60 mM | 0.0935 mL | 0.4677 mL | 0.9353 mL | 2.3383 mL | |
| 80 mM | 0.0701 mL | 0.3507 mL | 0.7015 mL | 1.7537 mL | |
| 100 mM | 0.0561 mL | 0.2806 mL | 0.5612 mL | 1.4030 mL |
2-Methoxycinnamic acid Related Classifications
HY-N1386 Related Classifications
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