8pyDTZ
Based on 3 publication(s) in Google Scholar
8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging.
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- Pureza: 98.0%
- No. CAS: 2351898-91-2
- Fòrmula: C24H18N4O
- Peso molecular:378.43
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years
* The compound is unstable in solutions, freshly prepared is recommended.
Publications Citing Use of MedChemExpress (MCE) 8pyDTZ
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Actividad biológica
Guide (The following is our recommended protocol. This protocol is only a guide and should be modified according to your specific needs).
Imaging Procedure[2]
1. Anesthetize the mouse and remove hair from the imaging area, then disinfect with 70% ethanol.
2. Inject the mouse intraperitoneally with 8pyDTZ working solution.
3. Immediately place the mouse in a bioluminescence imaging device and set the parameters.
4. Acquire bioluminescence images for 20 minutes.
5. Analyze the images using software such as ImageJ.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2351898-91-2
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Appearance Solid
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Peso molecular 378.43
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Fòrmula C24H18N4O
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Color Light brown to brown
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SMILES
O=C1C(CC2=CC=CC=C2)=NC3=C(C4=CC=NC=C4)NC(C5=CC=CC=C5)=CN31
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years * The compound is unstable in solutions, freshly prepared is recommended.
Publications (3)
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Journal Impact Factor
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Most Recent
Solvente y solubilidad
EtOH + HCl : 2 mg/mL (5.28 mM; ultrasonic and adjust pH to 2 with 1M HCl; DMSO can inactivate 8pyDTZ's activity)
H2O : < 0.1 mg/mL (insoluble; DMSO can inactivate 8pyDTZ's activity)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| EtOH + HCl | 1 mM | 2.6425 mL | 13.2125 mL | 26.4250 mL | 66.0624 mL |
| 5 mM | 0.5285 mL | 2.6425 mL | 5.2850 mL | 13.2125 mL |