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Referencia número: HY-U00211

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CS476

Name: CS476
Brand: MedChemExpress
SKU: HY-U00211
Availability: PreOrder

(Synonyms: NSC302998)

CS476 is a potent hypoglycaemic agent.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 41177-35-9
Fòrmula: C₂₄H₂₉N₃O₅S
Peso molecular:471.57

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

CS476 Chemical Structure

No. CAS: 41177-35-9

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Actividad biológica
- Descripciòn
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

CS476 is a potent hypoglycaemic agent.

In Vivo

In normal fasting dogs, rabbits, rats and mice the maximal hypoglycaemia produced by intravenous administration of CS476 is comparable on a weight basis to that produced by Glibenclamide. Randomized Latin square experiments in dogs show that 0.03 mg/kg orally of CS476 and of Glibenclamide cause the same maximal decrease of blood glucose and that CS476 has the shorter duration of action. CS476 has no hypoglycaemic effect in totally pancreatectomized dogs nor in streptozotocin diabetic dogs and rats. The insulin releasing activity is studied in dogs after intravenous and oral administration of equipotent doses of CS476, Tolbutamide and Glibenclamide^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 41177-35-9
Peso molecular 471.57
Fòrmula C₂₄H₂₉N₃O₅S
SMILES

O=C(C1=C(OCC2)C2=CC=C1)NCCC3=CC=C(S(=O)(NC(NC4CCCCC4)=O)=O)C=C3
Synonyms

NSC302998
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Jorgensen KD. The pharmacology of a new hypoglycaemic agent N-[4-(2-(2,3-dihydrobenzo(b)furan-m-carboxamido)-ethyl)-benzenesulphonyl]-N'-cyclohexylurea (NOVO CS 476). I. Pharmacological studies on the hypoglycaemic effect. Acta Pharmacol Toxicol (Copenh). 1977 Feb;40(2):216-26. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

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Calculadora de dilución

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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