AMC-01
Based on 1 Customer Validation
AMC-01 is a potent chemical probe that regulates eIF2-α activity. AMC-01 induces protein kinase RNA activation (PKR) kinase and nuclear factor κb (NF-κB). AMC-01 inhibits apoptosis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.38%
- No. CAS: 1047978-71-1
- Fòrmula: C27H27BrN2O6
- Peso molecular:555.42
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Actividad biológica
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Chemical Information
- Pureza y Documentación
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
AMC-01 (25 μM, 2 h) can inhibit apoptosis of rat neural progenitor cell CSM14.1 induced by Thapsigargin (HY-13433)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:CSM 14.1
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Concentration:25 μM
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Incubation Time:2 h
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Result:Increased phosphorylation of eIF2-α , p38 MAPK and NF-κB p65.
Chemical Information
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No. CAS 1047978-71-1
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Appearance Solid
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Peso molecular 555.42
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Fòrmula C27H27BrN2O6
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Color White to off-white
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SMILES
O=C(O)C(O)=O.COC1=CC=C(Br)C=C1CN2CCN(C(C3=CC=C(C4=CC=CC=C4)C=C3)=O)CC2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureza y Documentación
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Ficha de datos (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMC-01 Related Classifications
HY-114568 Related Classifications
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