Anticancer agent 107
Anticancer agent 107(Compd 11jc) has significant antitumor activity and can be used as an anticancer agent in the study of pulmonary metastatic melanoma.
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- No. CAS: 2397573-96-3
- Fòrmula: C24H19N3O4S
- Peso molecular:445.49
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| 4T1 | IC50 |
8.8 μM
Compound: 11jc
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Cytotoxicity against mouse 4T1 cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
Cytotoxicity against mouse 4T1 cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
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[PMID: 37084598] |
| B16-F10 | IC50 |
6.2 μM
Compound: 11jc
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Cytotoxicity against mouse B16-F10 cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
Cytotoxicity against mouse B16-F10 cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
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[PMID: 37084598] |
| CT26 | IC50 |
9.3 μM
Compound: 11jc
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Cytotoxicity against mouse CT26 cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
Cytotoxicity against mouse CT26 cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
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[PMID: 37084598] |
| MEF | IC50 |
>100 μM
Compound: 11jc
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Cytotoxicity against NF2-deficient mouse MEF cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
Cytotoxicity against NF2-deficient mouse MEF cells assessed as cell survival incubated for 24 hrs by alamarblue staining based analysis
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[PMID: 37084598] |
Chemical Information
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No. CAS 2397573-96-3
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Peso molecular 445.49
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Fòrmula C24H19N3O4S
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SMILES
N#CC(C/1=O)=C(NC(C2=C3SC4=C2CCCCC4)=O)N3C1=C\C(C5=CC=C(OC)C=C5)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 107 Related Classifications
HY-149951 Related Classifications
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