Anticancer agent 59
Anticancer agent 59 (compound 11) has inhibitory activity against kinds of cancer cell lines, especially in A549 with IC50 of 0.2 μM. Anticancer agent 59 induces apoptosis and an increase of Ca2+ and ROS in cancer cells. Anticancer agent 59 significantly decreases mitochondrial membrane potential. Anticancer agent 59 can suppress tumor growth in A549 mouse xenograft model.
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- No. CAS: 2366170-11-6
- Fòrmula: C42H59NO6
- Peso molecular:673.92
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
IC50: 0.2 μM in A549[1]
Chemical Information
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No. CAS 2366170-11-6
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Peso molecular 673.92
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Fòrmula C42H59NO6
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SMILES
C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CC[C@@](C)(C4)C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)C)=CC([C@]1([H])[C@@]6([C@@](C(C)([C@H](CC6)OC(CC)=O)C)([H])CC2)C)=O)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)