Anticancer agent 88
Anticancer agent 88 is a spirooxindole-furan derivative with anticancer activity. Anticancer agent 88 can be used for the research of breast adenocarcinoma and human liver cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C35H29BrCl2N2O3
- Peso molecular:676.43
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
Anticancer agent 88 (Compound 6d) potently inhibits the viability of MCF7 human breast adenocarcinoma cells with an IC50 of 4.3 μM/mL[1].
Anticancer agent 88 inhibits the viability of HepG2 human liver carcinoma cells with an IC50 of 6.9 μM/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Peso molecular 676.43
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Fòrmula C35H29BrCl2N2O3
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SMILES
O=C1NC2=C(C=CC(Cl)=C2)[C@@]13N4C([C@@H](C5=CC=C(C6=CC=C(Cl)C=C6)O5)[C@@H]3C(C7=CC=C(Br)C=C7)=O)CC8CCCCC48
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)