BCX 1470
BCX 1470 inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 217099-43-9
- Fòrmula: C14H10N2O2S2
- Peso molecular:302.37
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin)
BCX 1470 is serine protease inhibitor. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 217099-43-9
-
Peso molecular 302.37
-
Fòrmula C14H10N2O2S2
-
SMILES
N=C(C1=CC2=CC=C(OC(C3=CC=CS3)=O)C=C2S1)N
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)