BE2254
BE2254 is a compound with antipyretic and metabolic activity, which has the activity of regulating the febrile response and metabolism. BE2254 can reduce the metabolic and febrile activity induced by lipopolysaccharide in febrile rabbits, suggesting that it may regulate body temperature by acting on the α1-adrenergic receptor mechanism.
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- No. CAS: 40077-13-2
- Fòrmula: C19H21NO2
- Peso molecular:295.38
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 40077-13-2
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Peso molecular 295.38
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Fòrmula C19H21NO2
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SMILES
O=C1C(CCC2=C1C=CC=C2)CNCCC3=CC=C(C=C3)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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MTT Cell Proliferation Assay
The MTT assay is a colorimetric endpoint assay for estimating viable cell number, cell growth, cytotoxicity, or cell activation in cultured mammalian cells. Living cells reduce the yellow tetrazolium salt MTT into purple/blue formazan, while dead cells do not generate the same signal; the resulting color can be quantified with a multiwell spectrophotometer. MTT reduction is commonly interpreted as a readout of metabolic activity that often correlates with viable cell number, but it should not be treated as a direct cell-counting method unless the assay is optimized for the cell type and experimental condition. Studies show that MTT reduction can involve mitochondrial and non-mitochondrial reducing systems, and formazan may accumulate in intracellular lipid droplets rather than simply marking mitochondria.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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