BF-170
Based on 1 Customer Validation
BF-170 is a selective tau fibril binding agent with an EC50 of 221 nM. It exhibits good blood-brain barrier permeability, and after intravenous injection in mice, the concentration in brain tissue reaches 9.1% ID/g within 2 minutes (with a brain clearance rate of 0.25% ID/g after 30 minutes). BF-170 can be used as a probe for tau protein pathology imaging in Alzheimer's disease (AD). It plays an important role in early-stage AD research and holds potential for imaging studies of tau-related neurodegenerative diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.74%
- No. CAS: 22191-97-5
- Fòrmula: C15H12N2
- Peso molecular:220.27
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Almacenamiento:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Chemical Information
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No. CAS 22191-97-5
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Appearance Solid
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Peso molecular 220.27
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Fòrmula C15H12N2
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Color White to off-white
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SMILES
C1=CC=C2C(=C1)C=CC(=N2)C3=CC=C(C=C3)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
1 M HCl : ≥ 100 mg/mL (453.99 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1 M HCl | 1 mM | 4.5399 mL | 22.6994 mL | 45.3988 mL | 113.4971 mL |
| 5 mM | 0.9080 mL | 4.5399 mL | 9.0798 mL | 22.6994 mL | |
| 10 mM | 0.4540 mL | 2.2699 mL | 4.5399 mL | 11.3497 mL | |
| 15 mM | 0.3027 mL | 1.5133 mL | 3.0266 mL | 7.5665 mL | |
| 20 mM | 0.2270 mL | 1.1350 mL | 2.2699 mL | 5.6749 mL | |
| 25 mM | 0.1816 mL | 0.9080 mL | 1.8160 mL | 4.5399 mL | |
| 30 mM | 0.1513 mL | 0.7566 mL | 1.5133 mL | 3.7832 mL | |
| 40 mM | 0.1135 mL | 0.5675 mL | 1.1350 mL | 2.8374 mL | |
| 50 mM | 0.0908 mL | 0.4540 mL | 0.9080 mL | 2.2699 mL | |
| 60 mM | 0.0757 mL | 0.3783 mL | 0.7566 mL | 1.8916 mL | |
| 80 mM | 0.0567 mL | 0.2837 mL | 0.5675 mL | 1.4187 mL | |
| 100 mM | 0.0454 mL | 0.2270 mL | 0.4540 mL | 1.1350 mL |
BF-170 Related Classifications
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