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United States

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Referencia número: HY-150620

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BI-0282

BI-0282 (Compound 1) is a potent MDM2-p53 interaction inhibitor.

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No. CAS: 1883383-48-9
Fòrmula: C₃₀H₂₃Cl₂FN₄O₄
Peso molecular:593.43

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

BI-0282 Chemical Structure

No. CAS: 1883383-48-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

BI-0282 (Compound 1) is a potent MDM2-p53 interaction inhibitor^[1].

Chemical Information

No. CAS 1883383-48-9
Peso molecular 593.43
Fòrmula C₃₀H₂₃Cl₂FN₄O₄
SMILES

FC1=C(C=CC=C1[C@@H]([C@@H]2N3C4=C5C=CC(C(O)=O)=CC5=N3)[C@]6(C(NC7=C6C=CC(Cl)=C7)=O)N([C@H]2CO4)CC8CC8)Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ramharter J, et al. Synthesis of MDM2-p53 Inhibitor BI-0282 via a Dipolar Cycloaddition and Late-Stage Davis–Beirut Reaction. Organic Process Research & Development, 2022.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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